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English: Linda Buck’s research has transformed the field of odorant perception through the cloning of mammalian olfactory receptors. Together with Richard Axel, Buck developed an ingenious method to identify a G protein-coupled odorant receptor family of unprecedented size, comprising up to 1000 distinct genes members. Buck then used olfactory receptor genes as molecular tools to gain insight into the mechanisms and organisations strategies underlying odor perception. Her work showed that the olfactory epithelium is comprised of spatial zones that express different sets of receptor genes and that each zone is a mosaic of randomly interspersed neurons expressing different receptors. Buck then showed that individual olfactory neurons express a single receptor gene. In later work, Buck has documented the organization of olfactory axonal projections into the brain. Buck’s work has been recognised by award of the 2004 Nobel Prize.
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: Dr Linda Buck ForMemRS.jpg
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Captions

Linda B. Buck

Items portrayed in this file

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Linda B. Buck

inception

10 July 2015

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0.00625 second

focal length

105 millimetre

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current19:34, 22 January 2020Thumbnail for version as of 19:34, 22 January 20202,523 × 2,521 (2.96 MB)RosiestepFile:Dr Linda Buck ForMemRS.jpg cropped 32 % horizontally, 55 % vertically using CropTool with precise mode.

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